Last verified against: 0.5.4b · updated 2026-07-09

Ranger Pathfinder Poison Concoction Build Guide

Overview

A damage-over-time specialist that throws concoctions to stack poison from range. Took a real hit in recent balance changes to poison scaling specifically, so treat it as a solid transition build rather than the strongest possible league starter right now.

Tier Rating
B Tier
Best For
endgame
Est. Cost
medium
Core Mechanic
Poison Concoction / Ice Shot

Pros & Cons

Pros

  • Poison DoT is efficient against high-health bosses since it doesn't need repeated direct hits
  • Throwing concoctions keeps you at a safe distance, unlike melee-adjacent damage-over-time builds

Cons

  • Recent patches specifically nerfed poison Pathfinder's scaling, check current patch notes before committing currency
  • Damage-over-time playstyle means clear speed lags behind direct-hit builds like Deadeye's Twister

Ascendancy Nodes

  1. Path Seeker — Lets you choose one of three paths to start allocating passives from another class's starting point on the tree
  2. Running Assault — Reduces the movement penalty from using skills while moving, and prevents Heavy Stun while sprinting
  3. Relentless Pursuit — Grants invulnerability to being Slowed while sprinting
  4. Overwhelming Toxicity — Doubles the maximum number of Poison stacks an enemy can have, the signature node for poison-stacking builds
  5. Traveller's Wisdom — Grants attribute passive nodes extra options for damage, defense, or cost efficiency instead of just more passive points

Full Guide

Why This Ascendancy

A damage-over-time specialist that throws concoctions to stack poison from range. Took a real hit in recent balance changes to poison scaling specifically, so treat it as a solid transition build rather than the strongest possible league starter right now.

Putting It Together

Follow the passive tree priority and leveling guide sections above in order, most of this build’s power comes from hitting the right nodes at the right stage rather than rushing everything at once. Cross-check the ascendancy node names against the in-game tree before following this as a precise, click-by-click plan, especially for anything marked as not yet individually verified above.

Skill Gem Setup

Main Skill
Poison Concoction
Concentrated Poison · Sustained Damage
Secondary Skill
Ice Shot
Cold Penetration · Precision
Spirit Skill
Toxic Growth
Utility
Dash
Utility
Flame Wall

Gear Priority

Weapon Core
Poison damage dagger/wand

Damage over time multiplier

Amulet Recommended
Poison stack-cap bonus

Chaos damage %

Ring Luxury
Concoction charge bonus

Duration

Passive Tree Priority

Leveling Guide

Frequently Asked Questions

Is this still good after the poison nerfs?

It's a step down from its peak but still functional, best treated as a mid-investment transition build rather than a top-tier league starter right now.

Deadeye or Pathfinder?

Deadeye's Twister is the stronger, more forgiving league-start pick currently; Pathfinder suits players who specifically want a damage-over-time playstyle.

Related Guides

Sources cross-checked: aoeah.com 0.5 Tier List (poison Pathfinder nerf notes) · PoE2Wiki Fextralife Pathfinder page · Game8 Pathfinder ascendancy overview